TRENDS OF DRUG LICENSING IN CHINA: FROM BRING-IN TO GO-GLOBAL

Trends of drug licensing in China: From bring-in to go-global

Global medicine R&D has shown a stabilized trend after fleeting prosperity lately.Despite of discouraging whole picture, the role of China in cross-border out-licensing activities of medical therapeutics keeps rising, which started since 2020 and Lance further boosted in 2023.A holistic analysis of drug and technology licensing, involving Chinese e

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Differential effects of desvenlafaxine on hot flashes in women with breast cancer taking tamoxifen: a randomized controlled trial

Abstract Hot flashes (HF) are a common adverse event of prolonged tamoxifen use in women with estrogen receptor-positive breast cancer, impacting psychiatric health and quality of life.While desvenlafaxine does not interact with tamoxifen, its efficacy and safety in breast torpedo cancer patients remain unstudied.This phase 3, four-week, multi-cent

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Nonlinear Semi-Numeric and Finite Element Analysis of Three-Point Bending Tests of Notched Polymer Fiber-Reinforced Concrete Prisms

A nonlinear semi-numeric and finite element analysis of three-point bending tests of notched polymer fiber-reinforced concrete prisms was performed.The computational and experimental results were compared in terms of the load-displacement behavior.The vertical midspan displacement and the crack mouth opening displacement results were considered.The

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SAliBASE: A Database of Simulated Protein Alignments

Simulated alignments are alternatives to manually constructed multiple sequence alignments for evaluating performance of multiple sequence alignment tools.The importance of simulated sequences is recognized because their true evolutionary history is known, which is very helpful for reconstructing accurate phylogenetic trees Measuring Cup Sets and a

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